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Nagwa M. Professor Elwan is the author of more than 50 research articles on dermatopathology, acne, psoriasis, atopic dermatitis, lymphoma, and leprosy and has been guest speaker at many national and international dermatology meetings. Du kanske gillar. Lifespan David Sinclair Inbunden.
Skin Cancer—A World-Wide Perspective | JAMA | JAMA Network
Sobotta Atlas of Anatomy, Package, 16th ed. Inbunden Engelska, Spara som favorit. Skickas inom vardagar. Skickas inom vardagar specialorder. Over the last decades the incidence of skin cancers is dramatically increasing world-wide. The investigators state that eliminating or reducing exposure to known lifestyle and environmental risk factors can result in a drop of one-third to two-fifths of new cancer cases.
The investigators suggest that these variations reflect differences in the type of exposures and associated cancers and in the availability and use of screening services and diagnostic imaging by region.
For example, for skin cancer only, the highest overall incidence rates among both men The investigators attribute this to elevated risk but also to an increased detection of skin cancers, particularly nonmelanoma skin cancer, in these countries. Cancer is a significant cause of morbidity and mortality worldwide, with In the report, Bray et al summarize the estimated numbers of new cases and deaths by cancer type and point to the variations in the incidence and mortality rates observed in the world regions and individual countries.
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FIGURE 1 illustrates the distribution of all-cancer incidence and mortality according to world area for both sexes combined. Europe accounts for In contrast to other regions, the shares of cancer deaths in Asia When comparing incidence rates across regions, for men, the rate is 6-fold higher, from Among women, incidence rates vary nearly 4-fold, from Death rates per , persons vary from Data pulled from the report indicate that for men and women combined, lung cancer is the most commonly diagnosed cancer, at Of the total cancer deaths, Among men exclusively, lung cancer has the highest incidence, followed by prostate and colorectal cancers.
After lung cancer, liver and stomach cancers had the next-highest mortality rates in men. The investigators observed the diversity of cancer demonstrated by the variations in the magnitude and profile of the disease between and within world regions.
For example, specific types of cancer have a global footprint: lung, female breast, and colorectal cancers make up one-third of the cancer incidence and mortality burden worldwide and are the respective top 3 cancers in terms of incidence and within the top 5 in terms of mortality first, fifth, and second, respectively. Non-melanoma skin cancer: Appendageal tumours.
Skin cancer - a world-wide perspective. Heidelberg, DE: Springer, They have a variable, often unspecific clinical presentation and a wide histologic spectrum.
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According to their origin, cutaneous sweat gland tumours can be classified as eccrine, apocrine, eccrine and apocrine mixed origin , or composite adnexal tumours. Further, they can be classified as benign or malignant, tumours of the sweat ducts or of the sweat glands secretory apparatus. Carcinomas of the eccrine and apocrine glands are neoplasms with infiltrative and metastatic potential. Some malignancies have benign counterparts from which they must be differentiated.
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Features that suggest malignancy include asymmetry of the lesion, invasion, irregular arrangement of neoplastic cells, cytonuclear atypia and pleomorphism, and significantly increased mitotic activity in the presence of abnormal mitotic figures. Other sweat gland carcinomas present differently from any benign tumour.
Differentiating primary cutaneous sudoriferous carcinomas from metastatic carcinomas can often pose a serious challenge.